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Expression cloning of a rat liver Na(+)-independent organic anion transporter.

Using expression cloning in Xenopus laevis oocytes, we have isolated a cDNA encoding a rat liver organic anion-transporting polypeptide (oatp). The cloned oatp mediated Na(+)-independent uptake of sulfobromophthalein (BSP) which was Cl(-)-dependent in the presence of bovine serum albumin (BSA) at lo...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Jacquemin, E, Hagenbuch, B, Stieger, B, Wolkoff, A W, Meier, P J
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42900/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8278353/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.1.133
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