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Lateral Diffusion of Gα(s) in the Plasma Membrane Is Decreased after Chronic but not Acute Antidepressant Treatment: Role of Lipid Raft and Non-Raft Membrane Microdomains
GPCR signaling is modified both in major depressive disorder and by chronic antidepressant treatment. Endogenous Gα(s) redistributes from raft- to nonraft-membrane fractions after chronic antidepressant treatment. Modification of G protein anchoring may participate in this process. Regulation of Gα(...
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| Udgivet i: | Neuropsychopharmacology |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4289966/ https://ncbi.nlm.nih.gov/pubmed/25249058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2014.256 |
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