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Non-viral immune electrogene therapy induces potent antitumour responses and has a curative effect in murine colon adenocarcinoma and melanoma cancer models

Antitumour efficacy of electroporated pEEV, coding for granulocyte–macrophage colony-stimulating factor and the B7-1 costimulatory immune molecule (pEEVGmCSF-b7.1) in growing solid tumours, was investigated and compared with a standard plasmid. Application of pEEVGmCSF-b7.1 led to complete tumour re...

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Detaylı Bibliyografya
Yayımlandı:Gene Ther
Asıl Yazarlar: Forde, P F, Hall, L J, de Kruijf, M, Bourke, M G, Doddy, T, Sadadcharam, M, Soden, D M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4289754/
https://ncbi.nlm.nih.gov/pubmed/25373914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2014.95
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