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Prevalence of c.2268dup and detection of two novel alterations, c.670_672del and c.1186C>T, in the TPO gene in a cohort of Malaysian–Chinese with thyroid dyshormonogenesis

OBJECTIVES: The c.2268dup mutation in the thyroid peroxidase (TPO) gene is the most common TPO alteration reported in Taiwanese patients with thyroid dyshormonogenesis. The ancestors of these patients are believed to originate from the southern province of China. Our previous study showed that this...

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Detalhes bibliográficos
Publicado no:BMJ Open
Main Authors: Lee, Ching Chin, Harun, Fatimah, Jalaludin, Muhammad Yazid, Heh, Choon Han, Othman, Rozana, Junit, Sarni Mat
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4289740/
https://ncbi.nlm.nih.gov/pubmed/25564141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2014-006121
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