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Mutation Spectrum in TPO Gene of Bangladeshi Patients with Thyroid Dyshormonogenesis and Analysis of the Effects of Different Mutations on the Structural Features and Functions of TPO Protein through In Silico Approach

Although thyroid dyshormonogenesis (TDH) accounts for 10-20% of congenital hypothyroidism (CH), the molecular etiology of TDH is unknown in Bangladesh. Thyroid peroxidase (TPO) is most frequently associated with TDH and the present study investigated the spectrum of TPO mutations in Bangladeshi pati...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Begum, Mst. Noorjahan, Islam, Md Tarikul, Hossain, Shekh Rezwan, Bhuyan, Golam Sarower, Halim, Mohammad A., Shahriar, Imrul, Sarker, Suprovath Kumar, Haque, Shahinur, Konika, Tasnia Kawsar, Islam, Md. Sazzadul, Rahat, Asifuzzaman, Qadri, Syeda Kashfi, Sultana, Rosy, Begum, Suraiya, Sultana, Sadia, Saha, Narayan, Hasan, Mizanul, Hasanat, M. A., Banu, Hurjahan, Shekhar, Hossain Uddin, Chowdhury, Emran Kabir, Sajib, Abu A., Islam, Abul B. M. M. K., Qadri, Syed Saleheen, Qadri, Firdausi, Akhteruzzaman, Sharif, Mannoor, Kaiissar
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6409061/
https://ncbi.nlm.nih.gov/pubmed/30915365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/9218903
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