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Notch signaling in the malignant bone marrow microenvironment: implications for a niche-based model of oncogenesis

Fueled by the growing interest in stem cell biology and the promise of regenerative medicine, study of the hematopoietic stem cell (HSC) microenvironment has provided critical insights into normal and malignant hematopoiesis. Notch receptor signaling in this microenvironment is a critical regulator...

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Détails bibliographiques
Publié dans:Ann N Y Acad Sci
Auteurs principaux: Evans, Andrew G., Calvi, Laura M.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4289406/
https://ncbi.nlm.nih.gov/pubmed/25351294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nyas.12562
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