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Notch signaling in the malignant bone marrow microenvironment: implications for a niche-based model of oncogenesis

Fueled by the growing interest in stem cell biology and the promise of regenerative medicine, study of the hematopoietic stem cell (HSC) microenvironment has provided critical insights into normal and malignant hematopoiesis. Notch receptor signaling in this microenvironment is a critical regulator...

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Detalhes bibliográficos
Publicado no:Ann N Y Acad Sci
Main Authors: Evans, Andrew G., Calvi, Laura M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4289406/
https://ncbi.nlm.nih.gov/pubmed/25351294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nyas.12562
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