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Notch signaling in the malignant bone marrow microenvironment: implications for a niche-based model of oncogenesis

Fueled by the growing interest in stem cell biology and the promise of regenerative medicine, study of the hematopoietic stem cell (HSC) microenvironment has provided critical insights into normal and malignant hematopoiesis. Notch receptor signaling in this microenvironment is a critical regulator...

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Bibliographic Details
Published in:Ann N Y Acad Sci
Main Authors: Evans, Andrew G., Calvi, Laura M.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4289406/
https://ncbi.nlm.nih.gov/pubmed/25351294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nyas.12562
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