Phase 1/2 study of valproic acid and short-course radiotherapy plus capecitabine as preoperative treatment in low-moderate risk rectal cancer-V-shoRT-R3 (Valproic acid - short RadioTherapy - rectum 3rd trial)

BACKGROUND: Locally advanced rectal cancer (LARC) is a heterogeneous group of tumors where a risk-adapted therapeutic strategy is needed. Short-course radiotherapy (SCRT) is a more convenient option for LARC patients than preoperative long-course RT plus capecitabine. Histone-deacetylase inhibitors...

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Bibliographic Details
Published in:BMC Cancer
Main Authors: Avallone, Antonio, Piccirillo, Maria Carmela, Delrio, Paolo, Pecori, Biagio, Di Gennaro, Elena, Aloj, Luigi, Tatangelo, Fabiana, D’Angelo, Valentina, Granata, Cinzia, Cavalcanti, Ernesta, Maurea, Nicola, Maiolino, Piera, Bianco, Franco, Montano, Massimo, Silvestro, Lucrezia, Terranova Barberio, Manuela, Roca, Maria Serena, Di Maio, Massimo, Marone, Pietro, Botti, Gerardo, Petrillo, Antonella, Daniele, Gennaro, Lastoria, Secondo, Iaffaioli, Vincenzo R, Romano, Giovanni, Caracò, Corradina, Muto, Paolo, Gallo, Ciro, Perrone, Francesco, Budillon, Alfredo
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
Subjects:
Study Protocol
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4289397/
https://ncbi.nlm.nih.gov/pubmed/25421252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-875
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