Potentiation of the Antibacterial Effect of Methanamine by Acetohydroxamic Acid
In vitro testing shows nearly all strains of Proteus to be susceptible to methenamine. However, infection by urease-producing bacteria alkalinizes the urine in vivo and prevents generation of formaldehyde, the active metabolite, from methenamine. We have previously shown acetohydroxamic acid (AHA) t...
Uloženo v:
| Vydáno v: | Antimicrob Agents Chemother |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology (ASM)
1974
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC428928/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4840424/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.5.2.101 |
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