Potentiation of the Antibacterial Effect of Methanamine by Acetohydroxamic Acid

In vitro testing shows nearly all strains of Proteus to be susceptible to methenamine. However, infection by urease-producing bacteria alkalinizes the urine in vivo and prevents generation of formaldehyde, the active metabolite, from methenamine. We have previously shown acetohydroxamic acid (AHA) t...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Musher, Daniel M., Griffith, Donald P., Tyler, Michael, Woelfel, Alan
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1974
Soggetti:	Articles
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC428928/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4840424/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.5.2.101
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