Diversity-oriented synthesis and activity evaluation of substituted bicyclic lactams as anti-malarial against Plasmodium falciparum

BACKGROUND: Malaria remains the world’s most important devastating parasitic disease. Of the five species of Plasmodium known to infect and cause human malaria, Plasmodium falciparum is the most virulent and responsible for majority of the deaths caused by this disease. Mainstream drug therapy targe...

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Vydáno v:Malar J
Hlavní autoři: Sharma, Vijeta, Agarwal, Shalini, Madurkar, Sanjay M, Datta, Gaurav, Dangi, Poonam, Dandugudumula, Ramu, Sen, Subhabrata, Singh, Shailja
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4289231/
https://ncbi.nlm.nih.gov/pubmed/25431142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-13-467
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