Diversity-oriented synthesis and activity evaluation of substituted bicyclic lactams as anti-malarial against Plasmodium falciparum

BACKGROUND: Malaria remains the world’s most important devastating parasitic disease. Of the five species of Plasmodium known to infect and cause human malaria, Plasmodium falciparum is the most virulent and responsible for majority of the deaths caused by this disease. Mainstream drug therapy targe...

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Enregistré dans:
Détails bibliographiques
Publié dans:Malar J
Auteurs principaux: Sharma, Vijeta, Agarwal, Shalini, Madurkar, Sanjay M, Datta, Gaurav, Dangi, Poonam, Dandugudumula, Ramu, Sen, Subhabrata, Singh, Shailja
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4289231/
https://ncbi.nlm.nih.gov/pubmed/25431142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-13-467
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