Dynamic transcriptional and epigenomic reprogramming from pediatric nasal epithelial cells to induced pluripotent stem cells

BACKGROUND: Induced pluripotent stem cells (iPSCs) hold tremendous potential, both as a biological tool to uncover the pathophysiology of disease by creating relevant human cell models, and as a source of cells for cell-based therapeutic applications. Studying the reprogramming process will also pro...

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Detalhes bibliográficos
Publicado no:J Allergy Clin Immunol
Main Authors: Ji, Hong, Zhang, Xue, Oh, Sunghee, Mayhew, Christopher N., Ulm, Ashley, Somineni, Hari K., Ericksen, Mark, Wells, James M., Khurana Hershey, Gurjit K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4289122/
https://ncbi.nlm.nih.gov/pubmed/25441642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2014.08.038
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