GENETIC INTERFERENCE WITH PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR γ IN SMOOTH MUSCLE ENHANCES MYOGENIC TONE IN THE CEREBROVASCULATURE VIA A RHO KINASE-DEPENDENT MECHANISM

Myogenic responses by resistance vessels are a key component of autoregulation in brain, thus playing a crucial role in regulating cerebral blood flow and protecting the blood-brain barrier against potentially detrimental elevations in blood pressure. Although cerebrovascular disease is often accomp...

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Veröffentlicht in:Hypertension
Hauptverfasser: De Silva, T. Michael, Ketsawatsomkron, Pimonrat, Pelham, Christopher, Sigmund, Curt D., Faraci, Frank M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4289099/
https://ncbi.nlm.nih.gov/pubmed/25385762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.114.04541
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