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Characterization of a Nudix hydrolase from Deinococcus radiodurans with a marked specificity for (deoxy)ribonucleoside 5'-diphosphates

BACKGROUND: Nudix hydrolases form a protein family whose function is to hydrolyse intracellular nucleotides and so regulate their levels and eliminate potentially toxic derivatives. The genome of the radioresistant bacterium Deinococcus radiodurans encodes 25 nudix hydrolases, an unexpectedly large...

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Detalhes bibliográficos
Main Authors: Fisher, David I, Cartwright, Jared L, Harashima, Hideyoshi, Kamiya, Hiroyuki, McLennan, Alexander G
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC428907/
https://ncbi.nlm.nih.gov/pubmed/15147580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-5-7
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