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The g5R (D250) Gene of African Swine Fever Virus Encodes a Nudix Hydrolase That Preferentially Degrades Diphosphoinositol Polyphosphates

The African swine fever virus (ASFV) g5R gene encodes a protein containing a Nudix hydrolase motif which in terms of sequence appears most closely related to the mammalian diadenosine tetraphosphate (Ap(4)A) hydrolases. However, purified recombinant g5R protein (g5Rp) showed a much wider range of nu...

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Detalhes bibliográficos
Main Authors: Cartwright, Jared L., Safrany, Stephen T., Dixon, Linda K., Darzynkiewicz, Edward, Stepinski, Janusz, Burke, Richard, McLennan, Alexander G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC135849/
https://ncbi.nlm.nih.gov/pubmed/11773415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.3.1415-1421.2002
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