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Allosteric Activation of the RNF146 Ubiquitin Ligase by a Poly(ADP-ribosyl)ation Signal
Protein poly(ADP-ribosyl)ation (PARylation) plays a role in diverse cellular processes such as DNA repair, transcription, Wnt signaling, and cell death(1–6). Recent studies have shown that PARylation can serve as a signal for the polyubiquitination and degradation of several critical regulatory prot...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4289021/ https://ncbi.nlm.nih.gov/pubmed/25327252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13826 |
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