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Sterilizing Immunity Elicited by Neisseria meningitidis Carriage Shows Broader Protection than Predicted by Serum Antibody Cross-Reactivity in CEACAM1-Humanized Mice

Neisseria meningitidis asymptomatically colonizes the human upper respiratory tract but is also the cause of meningitis and severe septicemia. Carriage or disease evokes an immune response against the infecting strain. Hitherto, we have known little about the breadth of immunity induced by natural c...

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Vydáno v:Infect Immun
Hlavní autoři: Johswich, Kay O., McCaw, Shannon E., Strobel, Lea, Frosch, Matthias, Gray-Owen, Scott D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288889/
https://ncbi.nlm.nih.gov/pubmed/25368118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02495-14
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