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Sterilizing Immunity Elicited by Neisseria meningitidis Carriage Shows Broader Protection than Predicted by Serum Antibody Cross-Reactivity in CEACAM1-Humanized Mice

Neisseria meningitidis asymptomatically colonizes the human upper respiratory tract but is also the cause of meningitis and severe septicemia. Carriage or disease evokes an immune response against the infecting strain. Hitherto, we have known little about the breadth of immunity induced by natural c...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Main Authors: Johswich, Kay O., McCaw, Shannon E., Strobel, Lea, Frosch, Matthias, Gray-Owen, Scott D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288889/
https://ncbi.nlm.nih.gov/pubmed/25368118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02495-14
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