A Bivalent Typhoid Live Vector Vaccine Expressing both Chromosome- and Plasmid-Encoded Yersinia pestis Antigens Fully Protects against Murine Lethal Pulmonary Plague Infection

Live attenuated bacteria hold great promise as multivalent mucosal vaccines against a variety of pathogens. A major challenge of this approach has been the successful delivery of sufficient amounts of vaccine antigens to adequately prime the immune system without overattenuating the live vaccine. He...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Infect Immun
Autores principales: Galen, James E., Wang, Jin Yuan, Carrasco, Jose A., Lloyd, Scott A., Mellado-Sanchez, Gabriela, Diaz-McNair, Jovita, Franco, Olga, Buskirk, Amanda D., Nataro, James P., Pasetti, Marcela F.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2014
Materias:
Microbial Immunity and Vaccines
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288866/
https://ncbi.nlm.nih.gov/pubmed/25332120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02443-14
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares