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A Yersinia pestis guaBA mutant is attenuated in virulence and provides protection against plague in a mouse model of infection

There is a need to develop effective countermeasures for Yersinia pestis, the etiologic agent of plague and a potential bioterrorism agent. Salmonella and Shigella spp. deleted in the guaBA genes involved in guanine biosynthesis have been shown to be attenuated in vivo. In this study, we sought to d...

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Detalhes bibliográficos
Main Authors: Oyston, Petra C. F., Mellado-Sanchez, Gabriela, Pasetti, Marcela F., Nataro, James P., Titball, Richard W., Atkins, Helen S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857377/
https://ncbi.nlm.nih.gov/pubmed/20096773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micpath.2010.01.005
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