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A Yersinia pestis guaBA mutant is attenuated in virulence and provides protection against plague in a mouse model of infection

There is a need to develop effective countermeasures for Yersinia pestis, the etiologic agent of plague and a potential bioterrorism agent. Salmonella and Shigella spp. deleted in the guaBA genes involved in guanine biosynthesis have been shown to be attenuated in vivo. In this study, we sought to d...

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書誌詳細
主要な著者: Oyston, Petra C. F., Mellado-Sanchez, Gabriela, Pasetti, Marcela F., Nataro, James P., Titball, Richard W., Atkins, Helen S.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857377/
https://ncbi.nlm.nih.gov/pubmed/20096773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micpath.2010.01.005
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