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Plasmid-mediated quinolone resistance

Three mechanisms for plasmid-mediated quinolone resistance (PMQR) have been discovered since 1998. Plasmid genes qnrA, qnrB, qnrC, qnrD, qnrS, and qnrVC code for proteins of the pentapeptide repeat family that protects DNA gyrase and topoisomerase IV from quinolone inhibition. The qnr genes appear t...

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Détails bibliographiques
Publié dans:Microbiol Spectr
Auteurs principaux: Jacoby, George A., Strahilevitz, Jacob, Hooper, David C.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288778/
https://ncbi.nlm.nih.gov/pubmed/25584197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/microbiolspec.PLAS-0006-2013
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