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Mechanism of plasmid-mediated quinolone resistance

Quinolones are potent antibacterial agents that specifically target bacterial DNA gyrase and topoisomerase IV. Widespread use of these agents has contributed to the rise of bacterial quinolone resistance. Previous studies have shown that quinolone resistance arises by mutations in chromosomal genes....

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Detalhes bibliográficos
Main Authors: Tran, John H., Jacoby, George A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122823/
https://ncbi.nlm.nih.gov/pubmed/11943863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.082092899
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