tigaR: integrative significance analysis of temporal differential gene expression induced by genomic abnormalities

BACKGROUND: To determine which changes in the host cell genome are crucial for cervical carcinogenesis, a longitudinal in vitro model system of HPV-transformed keratinocytes was profiled in a genome-wide manner. Four cell lines affected with either HPV16 or HPV18 were assayed at 8 sequential time po...

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Veröffentlicht in:BMC Bioinformatics
Hauptverfasser: Miok, Viktorian, Wilting, Saskia M, van de Wiel, Mark A, Jaspers, Annelieke, van Noort, Paula I, Brakenhoff, Ruud H, Snijders, Peter JF, Steenbergen, Renske DM, van Wieringen, Wessel N
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Methodology Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288633/
https://ncbi.nlm.nih.gov/pubmed/25278371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-15-327
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