Targeting the SMO oncogene by miR-326 inhibits glioma biological behaviors and stemness

BACKGROUND: Few studies have associated microRNAs (miRNAs) with the hedgehog (Hh) pathway. Here, we investigated whether targeting smoothened (SMO) with miR-326 would affect glioma biological behavior and stemness. METHODS: To investigate the expression of SMO and miR-326 in glioma specimens and cel...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Du, Wenzhong, Liu, Xing, Chen, Lingchao, Dou, Zhijin, Lei, Xuhui, Chang, Liang, Cai, Jinquan, Cui, Yuqiong, Yang, Dongbo, Sun, Ying, Li, Yongli, Jiang, Chuanlu
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288524/
https://ncbi.nlm.nih.gov/pubmed/25173582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou217
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