VHL regulates the effects of miR-23b on glioma survival and invasion via suppression of HIF-1α/VEGF and β-catenin/Tcf-4 signaling

Aberrant microRNA expression has been implicated in the development of human cancers. Here, we investigated the oncogenic significance and function of miR-23b in glioma. We identified that the expression of miR-23b was elevated in both glioma samples and glioma cells, indicated by real-time polymera...

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Hlavní autoři: Chen, Lingchao, Han, Lei, Zhang, Kailiang, Shi, Zhendong, Zhang, Junxia, Zhang, Anling, Wang, Yongzhi, Song, Yijun, Li, Yongli, Jiang, Tao, Pu, Peiyu, Jiang, Chuanlu, Kang, Chunsheng
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2012
Témata:
Basic and Translational Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408255/
https://ncbi.nlm.nih.gov/pubmed/22649212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nos122
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