High β-catenin/Tcf-4 activity confers glioma progression via direct regulation of AKT2 gene expression

Recent data suggest that the β-catenin/Tcf-4 signaling pathway plays an important role in human cancer tumorigenesis. However, the mechanism of β-catenin/Tcf-4 signaling in tumorigenesis is poorly understood. In this study, we show that Tcf-4 protein levels were significantly elevated in high-grade...

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Hlavní autoři: Zhang, Junxia, Huang, Kai, Shi, Zhendong, Zou, Jian, Wang, Yingyi, Jia, Zhifan, Zhang, Anling, Han, Lei, Yue, Xiao, Liu, Ning, Jiang, Tao, You, Yongping, Pu, Peiyu, Kang, Chunsheng
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2011
Témata:
Basic and Translational Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107098/
https://ncbi.nlm.nih.gov/pubmed/21636708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nor034
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