Pim1 kinase is upregulated in glioblastoma multiforme and mediates tumor cell survival

BACKGROUND: The current therapy for glioblastoma multiforme (GBM), the most aggressive and common primary brain tumor of adults, involves surgery and a combined radiochemotherapy that controls tumor progression only for a limited time window. Therefore, the identification of new molecular targets is...

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Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Herzog, Susann, Fink, Matthias Alexander, Weitmann, Kerstin, Friedel, Claudius, Hadlich, Stefan, Langner, Sönke, Kindermann, Katharina, Holm, Tobias, Böhm, Andreas, Eskilsson, Eskil, Miletic, Hrvoje, Hildner, Markus, Fritsch, Michael, Vogelgesang, Silke, Havemann, Christoph, Ritter, Christoph Alexander, Meyer zu Schwabedissen, Henriette Elisabeth, Rauch, Bernhard, Hoffmann, Wolfgang, Kroemer, Heyo Klaus, Schroeder, Henry, Bien-Möller, Sandra
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2015
Soggetti:
Basic and Translational Investigations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288523/
https://ncbi.nlm.nih.gov/pubmed/25155357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou216
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