Nanoscale ligand spacing influences receptor triggering in T cells and NK cells

Bioactive nanoscale arrays were constructed to ligate activating cell surface receptors on T cells (the CD3 component of the TCR complex) and NK cells (CD16). These arrays are formed from biofunctionalized gold nanospheres with controlled interparticle spacing in the range 25 – 104 nm. Responses to...

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Udgivet i:Nano Lett
Main Authors: Delcassian, Derfogail, Depoil, David, Rudnicka, Dominika, Liu, Mengling, Davis, Daniel M., Dustin, Michael L., Dunlop, Iain E.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288448/
https://ncbi.nlm.nih.gov/pubmed/24125583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl403252x
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