Prostaglandin E(2) promotes MYCN non-amplified neuroblastoma cell survival via β-catenin stabilization

Amplification of MYCN is the most well-known prognostic marker of neuroblastoma risk classification, but still is only observed in 25% of cases. Recent evidence points to the cyclic adenosine monophosphate (cAMP) elevating ligand prostaglandin E(2) (PGE(2)) and β-catenin as two novel players in neur...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Jansen, Sepp R, Holman, Rian, Hedemann, Ilja, Frankes, Ewoud, Elzinga, Carolina R S, Timens, Wim, Gosens, Reinoud, de Bont, Eveline S, Schmidt, Martina
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288364/
https://ncbi.nlm.nih.gov/pubmed/25266063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12418
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