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RECQL1 and WRN DNA repair helicases: potential therapeutic targets and proliferative markers against cancers

RECQL1 and WRN helicases in the human RecQ helicase family participate in maintaining genome stability, DNA repair, replication, and recombination pathways in the cell cycle. They are expressed highly in rapidly proliferating cells and tumor cells, suggesting that they have important roles in the re...

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Detalles Bibliográficos
Publicado en:Front Genet
Main Authors: Futami, Kazunobu, Furuichi, Yasuhiro
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288340/
https://ncbi.nlm.nih.gov/pubmed/25620975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2014.00441
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