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Factors driving the aspirin exacerbated respiratory disease phenotype

BACKGROUND: Aspirin-exacerbated respiratory disease (AERD) is explained in part by overexpression of 5-lipoxygenase and leukotriene C(4) synthase (LTC(4)S), resulting in constitutive overproduction of cysteinyl leukotrienes (CysLTs) and driving the surge in CysLT production that occurs with aspirin...

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Detalhes bibliográficos
Publicado no:Am J Rhinol Allergy
Main Authors: Steinke, John W., Borish, Larry
Formato: Artigo
Idioma:Inglês
Publicado em: OceanSide Publications, Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288232/
https://ncbi.nlm.nih.gov/pubmed/25590316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2500/ajra.2015.29.4123
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