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Factors driving the aspirin exacerbated respiratory disease phenotype
BACKGROUND: Aspirin-exacerbated respiratory disease (AERD) is explained in part by overexpression of 5-lipoxygenase and leukotriene C(4) synthase (LTC(4)S), resulting in constitutive overproduction of cysteinyl leukotrienes (CysLTs) and driving the surge in CysLT production that occurs with aspirin...
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| Pubblicato in: | Am J Rhinol Allergy |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
OceanSide Publications, Inc.
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4288232/ https://ncbi.nlm.nih.gov/pubmed/25590316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2500/ajra.2015.29.4123 |
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