Novel RNA chaperone domain of RNA-binding protein La is regulated by AKT phosphorylation

The cellular function of the cancer-associated RNA-binding protein La has been linked to translation of viral and cellular mRNAs. Recently, we have shown that the human La protein stimulates IRES-mediated translation of the cooperative oncogene CCND1 in cervical cancer cells. However, there is littl...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nucleic Acids Res
Prif Awduron: Kuehnert, Julia, Sommer, Gunhild, Zierk, Avery W., Fedarovich, Alena, Brock, Alexander, Fedarovich, Dzmitry, Heise, Tilman
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2015
Pynciau:
RNA
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288197/
https://ncbi.nlm.nih.gov/pubmed/25520193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1309
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