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Topological constraints strongly affect chromatin reconstitution in silico
The fundamental building block of chromatin, and of chromosomes, is the nucleosome, a composite material made up from DNA wrapped around a histone octamer. In this study we provide the first computer simulations of chromatin self-assembly, starting from DNA and histone proteins, and use these to und...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4288149/ https://ncbi.nlm.nih.gov/pubmed/25432958 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1085 |
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