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PROPER: comprehensive power evaluation for differential expression using RNA-seq

Motivation: RNA-seq has become a routine technique in differential expression (DE) identification. Scientists face a number of experimental design decisions, including the sample size. The power for detecting differential expression is affected by several factors, including the fraction of DE genes,...

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Vydáno v:Bioinformatics
Hlavní autoři: Wu, Hao, Wang, Chi, Wu, Zhijin
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287952/
https://ncbi.nlm.nih.gov/pubmed/25273110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu640
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