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PGC1-α over-expression prevents metabolic alterations and soleus muscle atrophy in hindlimb unloaded mice

Prolonged skeletal muscle inactivity causes muscle fibre atrophy. Redox imbalance has been considered one of the major triggers of skeletal muscle disuse atrophy, but whether redox imbalance is actually the major cause or simply a consequence of muscle disuse remains of debate. Here we hypothesized...

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Publicat a:J Physiol
Autors principals: Cannavino, Jessica, Brocca, Lorenza, Sandri, Marco, Bottinelli, Roberto, Pellegrino, Maria Antonietta
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287741/
https://ncbi.nlm.nih.gov/pubmed/25128574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.275545
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