PGC1-α over-expression prevents metabolic alterations and soleus muscle atrophy in hindlimb unloaded mice

Prolonged skeletal muscle inactivity causes muscle fibre atrophy. Redox imbalance has been considered one of the major triggers of skeletal muscle disuse atrophy, but whether redox imbalance is actually the major cause or simply a consequence of muscle disuse remains of debate. Here we hypothesized...

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Vydáno v:J Physiol
Hlavní autoři: Cannavino, Jessica, Brocca, Lorenza, Sandri, Marco, Bottinelli, Roberto, Pellegrino, Maria Antonietta
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2014
Témata:
Muscle
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287741/
https://ncbi.nlm.nih.gov/pubmed/25128574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.275545
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