Isogambogenic acid induces apoptosis-independent autophagic cell death in human non-small-cell lung carcinoma cells

To overcome drug resistance caused by apoptosis deficiency in patients with non-small cell lung carcinoma (NSCLC), there is a need to identify other means of triggering apoptosis-independent cancer cell death. We are the first to report that isogambogenic acid (iso-GNA) can induce apoptosis-independ...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Yang, Jianhong, Zhou, Yongzhao, Cheng, Xia, Fan, Yi, He, Shichao, Li, Shucai, Ye, Haoyu, Xie, Caifeng, Wu, Wenshuang, Li, Chunyan, Pei, Heying, Li, Luyuan, Wei, Zhe, Peng, Aihua, Wei, Yuquan, Li, Weimin, Chen, Lijuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287727/
https://ncbi.nlm.nih.gov/pubmed/25571970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07697
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