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Epigenetic Heterogeneity in HIV-1 Latency Establishment

Despite prolonged antiretroviral therapy, HIV-1 persists as transcriptionally inactive proviruses. The HIV-1 latency remains a principal obstacle in curing AIDS. It is important to understand mechanisms by which HIV-1 latency is established to make the latent reservoir smaller. We present a molecula...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Matsuda, Yuka, Kobayashi-Ishihara, Mie, Fujikawa, Dai, Ishida, Takaomi, Watanabe, Toshiki, Yamagishi, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287722/
https://ncbi.nlm.nih.gov/pubmed/25572573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07701
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