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Aptamer-Based Detection of Disease Biomarkers in Mouse Models for Chagas Drug Discovery

Drug discovery initiatives, aimed at Chagas treatment, have been hampered by the lack of standardized drug screening protocols and the absence of simple pre-clinical assays to evaluate treatment efficacy in animal models. In this study, we used a simple Enzyme Linked Aptamer (ELA) assay to detect T....

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Podrobná bibliografie
Vydáno v:PLoS Negl Trop Dis
Hlavní autoři: de Araujo, Fernanda Fortes, Nagarkatti, Rana, Gupta, Charu, Marino, Ana Paula, Debrabant, Alain
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287562/
https://ncbi.nlm.nih.gov/pubmed/25569299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003451
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