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Aptamer-Based Detection of Disease Biomarkers in Mouse Models for Chagas Drug Discovery

Drug discovery initiatives, aimed at Chagas treatment, have been hampered by the lack of standardized drug screening protocols and the absence of simple pre-clinical assays to evaluate treatment efficacy in animal models. In this study, we used a simple Enzyme Linked Aptamer (ELA) assay to detect T....

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Bibliografiske detaljer
Udgivet i:PLoS Negl Trop Dis
Main Authors: de Araujo, Fernanda Fortes, Nagarkatti, Rana, Gupta, Charu, Marino, Ana Paula, Debrabant, Alain
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287562/
https://ncbi.nlm.nih.gov/pubmed/25569299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003451
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