Signaling Components of the 1α,25(OH)(2)D(3)-Dependent Pdia3 Receptor Complex Are Required for Wnt5a Calcium-Dependent Signaling

Wnt5a and 1α,25(OH)(2)D(3) are important regulators of endochondral ossification. In osteoblasts and growth plate chondrocytes, 1α,25(OH)(2)D(3) initiates rapid effects via its membrane-associated receptor protein disulfide isomerase A3 (Pdia3) in caveolae, activating phospholipase A(2) (PLA(2))-act...

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Bibliographic Details
Published in:Biochim Biophys Acta
Main Authors: Doroudi, Maryam, Olivares-Navarrete, Rene, Hyzy, Sharon L., Boyan, Barbara D., Schwartz, Zvi
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287416/
https://ncbi.nlm.nih.gov/pubmed/24946135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2014.06.006
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