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Transcriptional Control of an Essential Ribozyme in Drosophila Reveals an Ancient Evolutionary Divide in Animals

Ribonuclease P (RNase P) is an essential enzyme required for 5′-maturation of tRNA. While an RNA-free, protein-based form of RNase P exists in eukaryotes, the ribonucleoprotein (RNP) form is found in all domains of life. The catalytic component of the RNP is an RNA known as RNase P RNA (RPR). Eukary...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Manivannan, Sathiya N., Lai, Lien B., Gopalan, Venkat, Simcox, Amanda
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287351/
https://ncbi.nlm.nih.gov/pubmed/25569672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004893
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