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Adenosine analogs with covalently attached lipids have enhanced potency at A(1)-adenosine receptors
Chemically functionalized congeners of N(6)-phenyladenosine and I ,3-dipropyl-8-phenylxanthine have been covalently coupled to fatty acids, diglyceridcs, and a phospholipid. The lipid-drug conjugates inhibit R-[(3)H]-phenylisopropyladenosinc binding to A(1)-adcnosine receptors in rat cerebral cortex...
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| Publicado no: | FEBS Lett |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1987
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4287258/ https://ncbi.nlm.nih.gov/pubmed/3691809 |
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