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Betaxolol, a selective β(1)-adrenergic receptor antagonist, diminishes anxiety-like behavior during early withdrawal from chronic cocaine administration in rats

BACKGROUND: Anxiety has been indicated as one of the main symptoms of the cocaine withdrawal syndrome in human addicts and severe anxiety during withdrawal may potentially contribute to relapse. As alterations in noradrenergic transmission in limbic areas underlie withdrawal symptomatology for many...

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Detalhes bibliográficos
Publicado no:Prog Neuropsychopharmacol Biol Psychiatry
Main Authors: Rudoy, C.A., Van Bockstaele, E.J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287233/
https://ncbi.nlm.nih.gov/pubmed/17513029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pnpbp.2007.04.005
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