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Overexpression of CRF in the BNST diminishes dysphoria but not anxiety-like behavior in nicotine withdrawing rats

Smoking cessation leads to dysphoria and anxiety, which both increase the risk for relapse. This negative affective state is partly mediated by an increase in activity in brain stress systems. Recent studies indicate that prolonged viral vector-mediated overexpression of stress peptides diminishes s...

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Detalhes bibliográficos
Publicado no:Eur Neuropsychopharmacol
Main Authors: Qi, Xiaoli, Guzhva, Lidia, Yang, Zhihui, Febo, Marcelo, Shan, Zhiying, Wang, Kevin K. W., Bruijnzeel, Adriaan W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067082/
https://ncbi.nlm.nih.gov/pubmed/27461514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.euroneuro.2016.07.007
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