The biofilm matrix destabilizers, EDTA and DNaseI, enhance the susceptibility of nontypeable Hemophilus influenzae biofilms to treatment with ampicillin and ciprofloxacin

Nontypeable Hemophilus influenzae (NTHi) is a Gram-negative bacterial pathogen that causes chronic biofilm infections of the ears and airways. The biofilm matrix provides structural integrity to the biofilm and protects biofilm cells from antibiotic exposure by reducing penetration of antimicrobial...

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Detalhes bibliográficos
Publicado no:Microbiologyopen
Main Authors: Cavaliere, Rosalia, Ball, Jessica L, Turnbull, Lynne, Whitchurch, Cynthia B
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287182/
https://ncbi.nlm.nih.gov/pubmed/25044339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mbo3.187
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