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Colon specific drug delivery of tramadol HCl for chronotherapeutics of arthritis
OBJECTIVE: The objective of present work is to develop and evaluate a matrix system for Chronotherapeutic delivery of centrally acting of opioid analgesic (tramadol HCl) to treat nocturnal symptoms of arthritis using almond gum as carrier. MATERIALS AND METHODS: Matrix tablets of tramadol HCl were p...
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| Publicado no: | Int J Pharm Investig |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Medknow Publications & Media Pvt Ltd
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4286834/ https://ncbi.nlm.nih.gov/pubmed/25599032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2230-973X.147232 |
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