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A Novel Multilayered Multidisk Oral Tablet for Chronotherapeutic Drug Delivery
A Multilayered Multidisk Tablet (MLMDT) comprising two drug-loaded disks enveloped by three drug-free barrier layers was developed for use in chronotherapeutic disorders, employing two model drugs, theophylline and diltiazem HCl. The MLMDT was designed to achieve two pulses of drug release separated...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Hindawi Publishing Corporation
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3762207/ https://ncbi.nlm.nih.gov/pubmed/24024200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/569470 |
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