The Histone Deacetylase Inhibitor Trichostatin A Sensitizes Human Renal Carcinoma Cells to TRAIL-Induced Apoptosis through Down-Regulation of c-FLIP(L)

Histone acetylation plays a critical role in the regulation of transcription by altering the structure of chromatin, and it may influence the resistance of some tumor cells to tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) by regulating the gene expression of components of the...

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Publicat a:Biomol Ther (Seoul)
Autors principals: Han, Min Ho, Park, Cheol, Kwon, Taek Kyu, Kim, Gi-Young, Kim, Wun-Jae, Hong, Sang Hoon, Yoo, Young Hyun, Choi, Yung Hyun
Format: Artigo
Idioma:Inglês
Publicat: The Korean Society of Applied Pharmacology 2015
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286747/
https://ncbi.nlm.nih.gov/pubmed/25593641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2014.092
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